Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228934 | 0.96 | PKM (0.38) | NPC1RAB9ACASP3SENP7MAPT | |
| SCHEMBL4237676 | 0.94 | PNLIP (0.41) | NPC1RAB9ACASP3SENP7PNLIP | |
| SCHEMBL4238833 | 0.91 | PKM (0.38) | NPC1RAB9AMAPTPKMMCHR1 | |
| SCHEMBL4229247 | 0.87 | MCHR1 (0.45) | NPC1RAB9ASMN1; SMN2PKMMCHR1 | |
| SCHEMBL4237744 | 0.86 | PKM (0.38) | NPC1RAB9ACASP3SENP7MAPT | |
| SCHEMBL4236329 | 0.86 | PKM (0.38) | NPC1RAB9ACASP3SENP7MAPT | |
| SCHEMBL4233302 | 0.86 | PKM (0.38) | PNLIPMAPTPKMMCHR1MEN1 | |
| SCHEMBL4232426 | 0.85 | MCHR1 (0.40) | NPC1RAB9ACASP3SENP7MAPT | |
| SCHEMBL4239015 | 0.85 | PKM (0.43) | MAPTPKMMCHR1MEN1KMT2A | |
| SCHEMBL4237367 | 0.85 | MCHR1 (0.39) | MAPTSMN1; SMN2PKMMCHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |