Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19546812 | 0.84 | L3MBTL1 (0.58) | L3MBTL1KDM4ESMN1; SMN2MAOAALDH1A1 | |
| SCHEMBL18892996 | 0.82 | L3MBTL1 (0.51) | L3MBTL1KDM4ESMN1; SMN2MAOAALDH1A1 | |
| SCHEMBL719219 | 0.82 | L3MBTL1 (0.55) | L3MBTL1KDM4ESMN1; SMN2MAOAALDH1A1 | |
| SCHEMBL23430325 | 0.79 | L3MBTL1 (0.53) | L3MBTL1KDM4ESMN1; SMN2MAOAALDH1A1 | |
| SCHEMBL28812099 | 0.77 | L3MBTL1 (0.51) | L3MBTL1KDM4ESMN1; SMN2MAOAALDH1A1 | |
| SCHEMBL4092983 | 0.76 | L3MBTL1 (0.57) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL21913545 | 0.76 | L3MBTL1 (0.54) | L3MBTL1KDM4ESMN1; SMN2MAOAALDH1A1 | |
| SCHEMBL20019274 | 0.76 | L3MBTL1 (0.54) | L3MBTL1KDM4ESMN1; SMN2MAOAALDH1A1 | |
| SCHEMBL16648249 | 0.76 | L3MBTL1 (0.50) | L3MBTL1KDM4ESMN1; SMN2MAOAALDH1A1 | |
| SCHEMBL4794783 | 0.75 | L3MBTL1 (0.52) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104756-A1 | UREA DERIVATIVES AND THEIR THERAPEUTIC USE | SERENTIS LIMITED (GB) | 2008-09-04 | — | — | WO | disclosed |