Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794783 | 0.81 | L3MBTL1 (0.52) | L3MBTL1KDM4EKCNH2AHRHTT | |
| Hydrochloric Acid SCHEMBL4793023 | 0.80 | L3MBTL1 (0.51) | L3MBTL1KDM4EKCNH2AHRHTT | |
| SCHEMBL4095186 | 0.79 | PLK1 (0.46) | L3MBTL1KDM4EAHRRECQLALDH1A1 | |
| SCHEMBL719219 | 0.78 | L3MBTL1 (0.55) | L3MBTL1KDM4EKCNH2HTTRECQL | |
| SCHEMBL4742414 | 0.76 | L3MBTL1 (0.53) | L3MBTL1KDM4EKCNH2HTTRECQL | |
| SCHEMBL23430325 | 0.75 | L3MBTL1 (0.53) | L3MBTL1KDM4EKCNH2HTTRECQL | |
| SCHEMBL353910 | 0.75 | KCNH2 (0.58) | L3MBTL1KDM4EKCNH2AHRHTT | |
| Carbamic Acid SCHEMBL27823881 | 0.75 | L3MBTL1 (0.49) | L3MBTL1KDM4EKCNH2HTTRECQL | |
| SCHEMBL18892996 | 0.74 | L3MBTL1 (0.51) | L3MBTL1KDM4EKCNH2HTTRECQL | |
| SCHEMBL28812099 | 0.74 | L3MBTL1 (0.51) | L3MBTL1KDM4EKCNH2HTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156578-A1 | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents | DEBIOPHARM INTERNATIONAL SA (CH) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156578-A1 | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents | GAA, TFPI, DBI | L3MBTL1 2179/4885KDM4E 3209/4885KCNH2 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.