SCHEMBL4742450

SCHEMBL4742450

CC(=O)Nc1cc(N2CCN(C(C)=O)CC2)c(NC(C)=O)cc1/N=N/c1c(C#N)cnn1-c1nc(O)nc(O)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 9/20 0.38
CSNK2A2 P19784 8/20 0.38
CSNK2B P67870 8/20 0.38
LMNA P02545 3/20 0.36
BCL6 P41182 1/20 0.34
RET P07949 1/20 0.33
KCNH2 Q12809 4/20 0.32
GSK3B P49841 2/20 0.32
HIPK2 Q9H2X6 2/20 0.32
CSF1R P07333 1/20 0.32
DYRK3 O43781 1/20 0.32
CDK2 P24941 1/20 0.32
PIM3 Q86V86 1/20 0.32
KDR P35968 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
CASP1 P29466 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742442 0.79 MAPT (0.35) CSNK2A1CSNK2A2CSNK2BLMNAPIM3
SCHEMBL10101862 0.70 MAPK8 (0.40) CSNK2A1GSK3BHIPK2CDK2
SCHEMBL4742439 0.69 ALDH1A1 (0.38) LMNACSF1RTP53HPGDCASP1
SCHEMBL4742452 0.69 ALDH1A1 (0.37) CSNK2A1LMNACSF1RCDK2HPGD
SCHEMBL4742455 0.66 KCNH2 (0.36) KCNH2NPSR1
SCHEMBL4742432 0.64 HPGD (0.34) CSNK2A1HPGDSMN1; SMN2
SCHEMBL4743225 0.64 HPGD (0.34) CSNK2A1HPGDSMN1; SMN2
SCHEMBL10101999 0.64 KDM4E (0.36) LMNACDK2KDRHPGDNPSR1
SCHEMBL4742499 0.62 KDM4E (0.33) CSNK2A1GSK3BHIPK2CDK2TP53
SCHEMBL13069060 0.61 PDE10A (0.34) CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed