SCHEMBL4742583

SCHEMBL4742583

NC(=O)c1cnn(-c2ncccn2)c1N=Nc1c(O)n(-c2ccccc2)[nH]c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK2 O43353 1/20 0.40
MAPT P10636 6/20 0.36
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
RAB9A P51151 6/20 0.35
NPC1 O15118 5/20 0.35
TDP1 Q9NUW8 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CASP3 P42574 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
CYP3A4 P08684 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
HSP90AA1 P07900 1/20 0.35
LDHA P00338 1/20 0.35
SLC9A1 P19634 2/20 0.34
SLC9A2 Q9UBY0 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742563 0.82 MAPT (0.36) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL4742663 0.80 MAPT (0.38) RIPK2MAPTMEN1KMT2ACYP1A2
SCHEMBL4742658 0.77 LDHA (0.39) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL4742612 0.73 FFAR4 (0.36) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL4742602 0.72 MPL (0.40) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL4742171 0.69 PDE4A (0.32)
SCHEMBL15031100 0.69 NQO2 (0.55) MAPTMEN1KMT2ACYP2C9RAB9A
SCHEMBL10102102 0.68 RIPK2 (0.56) RIPK2MAPTKMT2ACYP1A2CYP2C19
SCHEMBL10101836 0.68 RIPK2 (0.56) RIPK2MAPTKMT2ACYP1A2CYP2C19
SCHEMBL4742166 0.67 KMT2A (0.37) RIPK2KMT2ATDP1SMN1; SMN2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed