SCHEMBL4742663

SCHEMBL4742663

O=C(O)c1cnn(-c2ccncc2)c1N=Nc1c(O)n(-c2ccccc2)[nH]c1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
POLB P06746 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NR4A3 Q92570 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
MPL P40238 2/20 0.37
AR P10275 1/20 0.37
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.34
RIPK2 O43353 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
TDP1 Q9NUW8 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742583 0.80 RIPK2 (0.40) MAPTPOLBL3MBTL1SMN1; SMN2MEN1
SCHEMBL4742563 0.72 MAPT (0.36) MAPTPOLBL3MBTL1SMN1; SMN2MEN1
SCHEMBL4742612 0.71 FFAR4 (0.36) MAPTL3MBTL1SMN1; SMN2MEN1KMT2A
SCHEMBL4742602 0.70 MPL (0.40) MAPTPOLBL3MBTL1SMN1; SMN2MEN1
SCHEMBL10998196 0.66 POLB (0.61) MAPTPOLBL3MBTL1SMN1; SMN2NR4A3
SCHEMBL10332024 0.64 RAB9A (0.48) MAPTPOLBL3MBTL1SMN1; SMN2NR4A3
SCHEMBL27681344 0.63 ALKBH1 (0.46) MAPTPOLBL3MBTL1SMN1; SMN2NR4A3
SCHEMBL6319617 0.63 MAPK1 (0.59) MAPTL3MBTL1SMN1; SMN2NR4A3MEN1
SCHEMBL13982997 0.63 RIPK2 (0.59) MAPTPOLBL3MBTL1SMN1; SMN2MEN1
SCHEMBL10102102 0.62 RIPK2 (0.56) MAPTPOLBSMN1; SMN2KMT2AKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed