Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742597 | 0.86 | EGLN1 (0.43) | EGLN1EGLN3 | |
| SCHEMBL4740471 | 0.80 | EGLN1 (0.42) | EGLN1EGLN3 | |
| SCHEMBL4997472 | 0.77 | EGLN1 (0.57) | EGLN1ALDH1A1LMNAEGLN3FTO | |
| SCHEMBL4740494 | 0.76 | HTT (0.65) | EGLN1ALDH1A1LMNAEGLN3FTO | |
| SCHEMBL4992247 | 0.74 | EGLN3 (0.62) | EGLN1ALDH1A1LMNAEGLN3 | |
| SCHEMBL4992084 | 0.72 | EGLN3 (0.46) | EGLN1ALDH1A1LMNAEGLN3FTO | |
| SCHEMBL4989785 | 0.71 | EGLN3 (0.60) | EGLN1ALDH1A1LMNAEGLN3 | |
| SCHEMBL4997520 | 0.69 | EGLN3 (0.59) | EGLN1EGLN3FTOKDM5BKDM2A | |
| SCHEMBL3926997 | 0.68 | EGLN1 (0.40) | EGLN1ALDH1A1LMNAEGLN3 | |
| SCHEMBL4996305 | 0.68 | EGLN3 (0.59) | EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |