Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.40 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740471 | 0.87 | EGLN1 (0.42) | EGLN1EGLN3OGFOD1EGLN2HIF1AN | |
| SCHEMBL4742622 | 0.86 | EGLN1 (0.42) | EGLN1EGLN3 | |
| SCHEMBL4993693 | 0.74 | EGLN1 (0.63) | EGLN1EGLN3OGFOD1EGLN2HIF1AN | |
| SCHEMBL3926997 | 0.72 | EGLN1 (0.40) | EGLN1EGLN3OGFOD1EGLN2HIF1AN | |
| SCHEMBL3917509 | 0.68 | EGLN1 (0.70) | EGLN1EGLN3OGFOD1EGLN2HIF1AN | |
| SCHEMBL4997472 | 0.66 | EGLN1 (0.57) | EGLN1EGLN3OGFOD1EGLN2HIF1AN | |
| SCHEMBL4740495 | 0.66 | EGLN1 (0.65) | EGLN1EGLN3OGFOD1EGLN2HIF1AN | |
| SCHEMBL4737673 | 0.66 | EGLN1 (0.65) | EGLN1EGLN3OGFOD1EGLN2HIF1AN | |
| SCHEMBL4996358 | 0.66 | EGLN1 (0.61) | EGLN1EGLN3OGFOD1EGLN2HIF1AN | |
| SCHEMBL3926482 | 0.65 | EGLN1 (0.58) | EGLN1EGLN3EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |