Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 6/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14104171 | 0.82 | SRC (0.43) | SRCMAPK1EP300MAPK14PKM | |
| SCHEMBL23069262 | 0.81 | CYP19A1 (0.47) | SRCMAPK1EP300MAPK14PKM | |
| SCHEMBL16033032 | 0.78 | GGPS1 (0.48) | SRCMAPK1EP300L3MBTL1 | |
| SCHEMBL14788175 | 0.78 | MAPK1 (0.51) | SRCMAPK1EP300MAPK14PKM | |
| SCHEMBL16612622 | 0.76 | MAPK1 (0.46) | SRCMAPK1EP300MAPK14PKM | |
| SCHEMBL16612208 | 0.75 | MAPK1 (0.45) | SRCMAPK1EP300MAPK14PKM | |
| SCHEMBL15121329 | 0.75 | SRC (0.47) | SRCMAPK1EP300MAPK14PKM | |
| SCHEMBL18839729 | 0.75 | PKM (0.60) | MAPK1PKMATMHSD17B10ALDH1A1 | |
| SCHEMBL18839745 | 0.75 | MAPK1 (0.53) | MAPK1PKMATMHSD17B10ALDH1A1 | |
| SCHEMBL12847886 | 0.74 | SRC (0.44) | SRCMAPK1EP300MAPK14PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096127-A2 | BICYCLO[2.2.1]HEPT-7-YLAMINE DERIVATIVES AND THEIR USE AS M3 MUSCARINIC RECEPTOR MODULATORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |