SCHEMBL4742764

SCHEMBL4742764

N#Cc1cnn(-c2ncccn2)c1N=NC(C(=O)Nc1ccccc1Cl)c1nc2ccccc2c(=O)[nH]1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
PDE9A O76083 7/20 0.36
MEN1 O00255 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MALT1 Q9UDY8 3/20 0.34
PARP1 P09874 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
POLB P06746 1/20 0.32
PKM P14618 1/20 0.32
PDE5A O76074 3/20 0.32
PDE1B Q01064 3/20 0.32
PDE4D Q08499 3/20 0.32
PDE4A P27815 2/20 0.32
PDE4B Q07343 2/20 0.32
PDE4C Q08493 2/20 0.32
PDE7A Q13946 1/20 0.32
PDE10A Q9Y233 1/20 0.32
PDE8A O60658 1/20 0.32
G6PD P11413 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742774 0.93 LMNA (0.35) KMT2APDE9AMEN1KDM4EMALT1
SCHEMBL10280956 0.92 PARP1 (0.34) KMT2AMEN1KDM4EMALT1PARP1
SCHEMBL4779664 0.91 PARP1 (0.34) KMT2AMEN1KDM4EMALT1PARP1
SCHEMBL4742753 0.91 PARP1 (0.35) KMT2APDE9AMEN1KDM4EPARP1
SCHEMBL4779837 0.91 PARP1 (0.36) KMT2AKDM4EMALT1PARP1PARP2
SCHEMBL4742760 0.90 G6PD (0.39) KMT2APDE9AKDM4EMALT1PARP1
SCHEMBL4742752 0.90 MALT1 (0.33) KMT2APDE9AMEN1KDM4EMALT1
SCHEMBL4742716 0.89 PDE9A (0.41) PDE9APARP1PARP2G6PDALDH1A1
SCHEMBL4742750 0.89 KDM4E (0.41) KMT2APDE9AMEN1KDM4EMALT1
SCHEMBL4770886 0.88 MAPT (0.38) PDE9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed