SCHEMBL474297

SCHEMBL474297

CCCCCCCCCCCCN1CCC(C(N)=O)CC1

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.68
SMN1; SMN2 Q16637 2/20 0.62
GNAI3 P08754 8/20 0.59
GNAO1 P09471 8/20 0.59
GNAI1 P63096 8/20 0.59
KCNH2 Q12809 1/20 0.58
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17351140 1.00 BCHE (0.68) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL7131574 1.00 BCHE (0.68) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL7137293 1.00 BCHE (0.68) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL3933177 1.00 BCHE (0.68) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL30444781 1.00 BCHE (0.68) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL7135236 1.00 BCHE (0.68) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL3687400 0.98 BCHE (0.65) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL5227695 0.93 SMN1; SMN2 (0.67) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL28290338 0.90 BCHE (0.83) BCHESMN1; SMN2GNAI3GNAO1GNAI1
SCHEMBL28290336 0.90 BCHE (0.83) BCHESMN1; SMN2GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112206-B1 Polymer Composition ROHM & HAAS (US) 2016-06-29 EP disclosed
EP-2166043-B1 Thickener composition and method for thickening aqueous systems ROHM & HAAS (US) 2016-04-27 EP disclosed
EP-2166044-B1 Thickened compositions and method for thickening aqueous polymer compositions ROHM & HAAS (US) 2012-02-01 EP disclosed
US-20110281980-A1 Thickener composition and method for thickening aqueous systems BOBSEIN BARRETT RICHARD (US) 2011-11-17 US disclosed
US-8034869-B2 Thickened compositions and method for thickening aqueous polymer compositions ROHM AND HAAS COMPANY (US) 2011-10-11 US disclosed
US-7985795-B2 Thickener composition and method for thickening aqueous systems ROHM AND HAAS COMPANY (US) 2011-07-26 US disclosed
EP-1972665-B1 Thickener composition and method for thickening aqueous systems ROHM & HAAS (US) 2011-04-27 EP disclosed
US-20100286434-A1 Ethylenically unsaturated monomers for thickener compositions BOBSEIN BARRETT RICHARD 2010-11-11 US disclosed
US-20100261813-A1 Thickener composition and method for thickening aqueous systems BOBSEIN BARRETT RICHARD 2010-10-14 US disclosed
US-20100227953-A1 Thickened compositions and method for thickening aqueous polymer compositions ROHM AND HAAS COMPANY 2010-09-09 US disclosed
US-7741402-B2 Thickener composition and method for thickening aqueous systems ROHM AND HAAS COMPANY (US) 2010-06-22 US disclosed
US-20100076145-A1 Thickener composition and method for thickening aqueous systems ROHM AND HAAS COMPANY 2010-03-25 US disclosed
EP-2166044-A1 Thickened compositions and method for thickening aqueous polymer compositions Rohm and Haas Company (US) 2010-03-24 EP disclosed
EP-2166043-A2 Thickener composition and method for thickening aqueous systems Rohm and Haas Company (US) 2010-03-24 EP disclosed
EP-2112206-A1 Polymer Composition Rohm and Haas Company (US) 2009-10-28 EP disclosed
US-20080234411-A1 Thickener composition and method for thickening aqueous systems ROHM AND HAAS COMPANY 2008-09-25 US disclosed
EP-1972665-A2 Thickener composition and method for thickening aqueous systems Rohm and Haas Company (US) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286434-A1 Ethylenically unsaturated monomers for thickener compositions ELOVL1, ELOVL6, ELOVL5 BCHE 1902/4885SMN1; SMN2 1519/4885GNAI3 4426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.