SCHEMBL4742972

SCHEMBL4742972

CC(=O)C(N=Nc1c(C#N)cnn1-c1ncccn1)C(=O)Nc1cccc2cccnc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAPT P10636 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
PKM P14618 1/20 0.38
CASP3 P42574 2/20 0.37
SENP8 Q96LD8 2/20 0.37
SENP7 Q9BQF6 2/20 0.37
NLN Q9BYT8 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HTT P42858 2/20 0.37
TP53 P04637 2/20 0.37
SLC40A1 Q9NP59 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SENP6 Q9GZR1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742963 0.88 HTT (0.36) POLBMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL4742936 0.87 LMNA (0.38) POLBKMT2AMAPTPKMALDH1A1
SCHEMBL4742942 0.86 HTT (0.36) MEN1KMT2AMAPTSMN1; SMN2CASP3
SCHEMBL4781297 0.85 PANK3 (0.34) PKMKDR
SCHEMBL4742945 0.84 IRAK4 (0.38) MEN1KMT2AMAPTSMN1; SMN2PKM
SCHEMBL4742957 0.84 GFER (0.40) POLBMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL4781307 0.84 GRM4 (0.32) ALDH1A1HPGD
SCHEMBL4742955 0.84 KDM4E (0.41) POLBTDP1MEN1KMT2ASMN1; SMN2
SCHEMBL4742949 0.84 PKM (0.39) MEN1KMT2AMAPTSMN1; SMN2PKM
SCHEMBL4743018 0.80 IRAK4 (0.42) POLBTDP1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed