SCHEMBL4742973

SCHEMBL4742973

Cc1ccccc1NC(=O)C(N=Nc1c(C#N)cnn1-c1ncccn1)C(=O)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
KMT2A Q03164 1/20 0.36
PKM P14618 1/20 0.36
POLB P06746 2/20 0.34
HPGD P15428 2/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PGR P06401 1/20 0.32
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
SCN3A Q9NY46 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742936 0.90 LMNA (0.38) LMNARAB9ANPC1KMT2APKM
SCHEMBL4780174 0.81 GFER (0.41) RAB9ANPC1KMT2APKMPOLB
SCHEMBL4780194 0.81 GFER (0.40) RAB9ANPC1KMT2APKMPOLB
SCHEMBL4742942 0.81 HTT (0.36) RAB9ANPC1KMT2AHPGDHTT
SCHEMBL4742949 0.80 PKM (0.39) LMNAKMT2APKMHPGDPTGS1
SCHEMBL4742945 0.79 IRAK4 (0.38) RAB9ANPC1KMT2APKMPTGS1
SCHEMBL4742957 0.79 GFER (0.40) RAB9ANPC1KMT2APOLBCYP1A2
SCHEMBL4742963 0.79 HTT (0.36) LMNARAB9ANPC1KMT2APOLB
SCHEMBL4742955 0.79 KDM4E (0.41) LMNAKMT2APOLBHPGDCYP1A2
SCHEMBL4742753 0.78 PARP1 (0.35) LMNAKMT2APKMPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed