SCHEMBL4743012

SCHEMBL4743012

C=CCc1ccc(C(N)C(=O)O)c(-c2ccc(C(=O)CN)c(CC=C)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 14/20 0.44
GABRB2 P47870 14/20 0.44
ALOX5 P09917 6/20 0.44
CNR2 P34972 6/20 0.44
CNR1 P21554 3/20 0.44
MEN1 O00255 2/20 0.44
GAA P10253 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
GABRA2 P47869 2/20 0.44
POLB P06746 1/20 0.44
GABRB1 P18505 1/20 0.44
RXRA P19793 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
SIRT3 Q9NTG7 1/20 0.44
PTGS2 P35354 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4744172 0.99 GABRA1 (0.44) GABRA1GABRB2ALOX5CNR2CNR1
Hydrochloric Acid SCHEMBL4744799 0.85 MEN1 (0.38) GABRA1GABRB2ALOX5CNR2CNR1
SCHEMBL4740881 0.84 GABRA1 (0.64) GABRA1GABRB2ALOX5CNR2CNR1
Hydrochloric Acid SCHEMBL4741019 0.84 GABRA1 (0.63) GABRA1GABRB2ALOX5CNR2CNR1
SCHEMBL4743014 0.80 ALOX5 (0.60) GABRA1GABRB2ALOX5CNR2CNR1
Hydrochloric Acid SCHEMBL4744175 0.79 ALOX5 (0.59) GABRA1GABRB2ALOX5CNR2CNR1
Hydrochloric Acid SCHEMBL4740882 0.76 GABRA1 (0.41) GABRA1GABRB2ALOX5CNR2CNR1
SCHEMBL4744356 0.74 GABRA1 (0.62) GABRA1GABRB2ALOX5CNR2CNR1
Hydrochloric Acid SCHEMBL4742205 0.73 GABRA1 (0.60) GABRA1GABRB2ALOX5CNR2CNR1
Hydrochloric Acid SCHEMBL4787217 0.73 GABRA1 (0.41) GABRA1GABRB2ALOX5CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008099994-A1 BIPHENYL DIOL DERIVATIVES AND COMPOSITIONS COMPRISING THE SAME AS AN ACTIVE INGREDIENT BIOSPECTRUM INC. (KR) 2008-08-21 WO disclosed