Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638920 | 0.93 | CTNNB1 (0.58) | MAPTHPGDRAB9ACTNNB1MEN1 | |
| SCHEMBL2559974 | 0.90 | HPGD (0.58) | MAPTHPGDRAB9ACTNNB1MEN1 | |
| SCHEMBL6630321 | 0.88 | PARP10 (0.62) | MAPTHPGDRAB9ACTNNB1MEN1 | |
| SCHEMBL3179214 | 0.87 | CTNNB1 (0.67) | MAPTRAB9ACTNNB1MEN1KMT2A | |
| SCHEMBL29679671 | 0.87 | CTNNB1 (0.67) | MAPTRAB9ACTNNB1MEN1KMT2A | |
| SCHEMBL1555274 | 0.87 | SMN1; SMN2 (0.55) | MAPTHPGDRAB9ACTNNB1MEN1 | |
| SCHEMBL11604077 | 0.86 | CTNNB1 (0.51) | MAPTHPGDRAB9ACTNNB1MEN1 | |
| SCHEMBL19524204 | 0.86 | SCN8A (0.53) | MAPTCTNNB1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL8136102 | 0.85 | CTNNB1 (0.65) | MAPTRAB9ACTNNB1MEN1KMT2A | |
| SCHEMBL2303571 | 0.84 | MAPT (0.60) | MAPTHPGDCTNNB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099415-A1 | NOVEL SUBSTITUTED BIS-1, 2, 4-TRIOXANES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-08-21 | — | — | WO | disclosed |