Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.53 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638920 | 0.93 | CTNNB1 (0.58) | CTNNB1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL29679671 | 0.87 | CTNNB1 (0.67) | CTNNB1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL3179214 | 0.87 | CTNNB1 (0.67) | CTNNB1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL11604077 | 0.86 | CTNNB1 (0.51) | CTNNB1KMT2AMEN1PNLIPLMNA | |
| SCHEMBL4743129 | 0.86 | MAPT (0.62) | CTNNB1KMT2AMEN1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8136102 | 0.85 | CTNNB1 (0.65) | CTNNB1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL2303571 | 0.84 | MAPT (0.60) | CTNNB1KMT2AMEN1PNLIPLMNA | |
| SCHEMBL7755868 | 0.84 | LMNA (0.51) | CTNNB1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL9367885 | 0.84 | PTGER4 (0.51) | SCN8ASCN10APNLIPALDH1A1SMN1; SMN2 | |
| SCHEMBL2865011 | 0.84 | CTNNB1 (0.58) | SCN8ASCN10ACTNNB1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239134-A1 | PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2017-11-01 | — | — | EP | disclosed |
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |