Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743129 | 0.90 | MAPT (0.62) | HPGDMAPTRAB9AHTTKDM4E | |
| SCHEMBL920326 | 0.88 | SRD5A2 (0.59) | HPGDMAPTHTTKDM4EHSD17B10 | |
| SCHEMBL28411450 | 0.88 | CTNNB1 (0.66) | HPGDMAPTRAB9AHTTKDM4E | |
| SCHEMBL9252102 | 0.84 | CTNNB1 (0.67) | HPGDMAPTRAB9AHTTKDM4E | |
| SCHEMBL1798 | 0.84 | CTNNB1 (0.71) | HPGDMAPTRAB9AHTTKDM4E | |
| SCHEMBL2863787 | 0.83 | HTT (0.69) | HPGDMAPTRAB9AHTTKDM4E | |
| SCHEMBL366 | 0.83 | HTT (0.59) | HPGDMAPTRAB9AHTTKDM4E | |
| SCHEMBL30775034 | 0.83 | HTT (0.59) | HPGDMAPTRAB9AHTTKDM4E | |
| SCHEMBL12857834 | 0.83 | PYGM (0.57) | HPGDHTTKDM4EHSD17B10ALDH1A1 | |
| Bicarbonate SCHEMBL236889 | 0.82 | CTNNB1 (0.69) | HPGDMAPTRAB9AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |
| EP-0003893-B1 | NOVEL DIBENZ (B,F) OXEPIN AND DIBENZO (B,F) THIEPIN COMPOUNDS AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dainippon Pharmaceutical Co., Ltd. (JP) | 1981-11-04 | — | — | EP | disclosed |
| US-4238620-A | ANTIPYRETICS; ANALGESICS; ANTIINFLAMMATORY AGENTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1980-12-09 | — | — | US | disclosed |
| EP-0003893-A1 | Novel dibenz (b,f) oxepin and dibenzo (b,f) thiepin compounds and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1979-09-05 | — | — | EP | disclosed |