SCHEMBL4743256

SCHEMBL4743256

COc1ccccc1NC(=O)Cc1nc2ccccc2o1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
LMNA P02545 3/20 0.53
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
P2RY14 Q15391 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
PKM P14618 1/20 0.50
HTT P42858 1/20 0.50
GAA P10253 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MPO P05164 1/20 0.49
ALDH1A1 P00352 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11835830 0.78 MEN1 (0.61) TP53SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL14310604 0.77 RAB9A (0.54) TP53SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL5624696 0.77 MAPT (0.54) TP53SMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL12561522 0.75 NPC1 (0.51) TP53SMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL13101605 0.74 RAB9A (0.50) TP53SMN1; SMN2LMNAKMT2AP2RY14
SCHEMBL13342377 0.74 NPC1 (0.50) TP53SMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL4044940 0.74 ADRB2 (0.43) TP53SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL2007035 0.73 MEN1 (0.76) SMN1; SMN2LMNAMEN1KMT2AHTT
SCHEMBL10255090 0.73 GLA (0.64) SMN1; SMN2LMNAMEN1KMT2AL3MBTL1
SCHEMBL6169172 0.73 MEN1 (0.83) SMN1; SMN2LMNAMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed