SCHEMBL4743281

SCHEMBL4743281

Cc1ccc(C#N)c(C#N)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 4/20 0.39
MAPT P10636 3/20 0.39
ALOX15 P16050 3/20 0.39
HSD17B10 Q99714 3/20 0.39
CASP1 P29466 2/20 0.39
CASP7 P55210 2/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
RAB9A P51151 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 2/20 0.36
APOBEC3G Q9HC16 1/20 0.36
AR P10275 6/20 0.35
GRM6 O15303 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29913598 1.00 TSHR (0.44) TSHRALDH1A1KDM4EMAPTALOX15
SCHEMBL10766410 0.91 TSHR (0.44) TSHRALDH1A1KDM4EMAPTALOX15
SCHEMBL17570551 0.85 TSHR (0.42) TSHRALDH1A1KDM4EHPGDAR
SCHEMBL17570552 0.83 TSHR (0.46) TSHRALDH1A1KDM4EMAPTALOX15
SCHEMBL19914848 0.82 CYP1A2 (0.42) TSHRALDH1A1KDM4EMAPTALOX15
Hexamethylbenzene SCHEMBL4271177 0.82 TSHR (0.44) TSHRALDH1A1KDM4EHPGDAR
SCHEMBL8852021 0.81 TSHR (0.44) TSHRALDH1A1KDM4EMAPTALOX15
SCHEMBL29398131 0.81 TSHR (0.44) TSHRALDH1A1KDM4EMAPTALOX15
SCHEMBL3954053 0.80 TSHR (0.48) TSHRALDH1A1KDM4EMAPTALOX15
SCHEMBL11339660 0.77 TRPV4 (0.41) TSHRALDH1A1KDM4EHPGDAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785841-B2 Compound, display panel and display apparatus WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-10-10 US disclosed
US-11758809-B2 Compound, display panel, and display apparatus Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-09-12 US disclosed
US-11751474-B2 Compound and organic light emitting display device WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-09-05 US disclosed
CN-108586531-B 2-phosphonoquinoxaline compound and preparation method thereof 郑州大学 2020-03-31 CN disclosed
CN-110026243-A A kind of preparation method and applications of loaded type silicon phthalocyanine photochemical catalyst 青岛大学 2019-07-19 CN disclosed
US-20170256720-A1 ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR KYULUX, INC. (JP) 2017-09-07 US disclosed
US-9502668-B2 Organic light-emitting device, and light-emitting material and compound used therefor KYULUX, INC. (JP) 2016-11-22 US disclosed
US-20150105564-A1 ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR KYULUX, INC. (JP) 2015-04-16 US disclosed
WO-2008110747-A1 PHTHALOCVANINES AND THEIR USE IN INK-JET PRINTING FUJIFILM IMAGING COLORANTS LIMITED (GB) 2008-09-18 WO disclosed
US-5756247-A PHOTOCONDUCTOR OBTAINED BY HYDROXYLATION WITH ACID PASTING GALLIUM PHTHALOCYANINE; CHARGEABILITY, IMAGE; SEMICONDUCTOR LASER PRINTER FUJI XEROX CO., LTD. (JP) 1998-05-26 US disclosed
US-5663327-A Hydroxygallium phthalocyanine crystal, process for producing the same, and electrophotographic photoreceptor containing the same FUJI XEROX CO., LTD. (JP) 1997-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170256720-A1 ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR CRY1, WEE1, OR51E2 TSHR 3283/4885ALDH1A1 80/4885KDM4E 3233/4885
US-11785841-B2 Compound, display panel and display apparatus C1S, CDK20, CEP170 TSHR 3137/4885ALDH1A1 1239/4885KDM4E 3873/4885
US-11751474-B2 Compound and organic light emitting display device L1CAM, C1S, CCNE2 TSHR 2920/4885ALDH1A1 57/4885KDM4E 3712/4885
US-11758809-B2 Compound, display panel, and display apparatus C1S, C3AR1, DRD3 TSHR 3170/4885ALDH1A1 928/4885KDM4E 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.