Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 9/20 | 0.47 |
| ▸ | SCN4A | P35499 | 3/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768133 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL64093 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL3073425 | 0.84 | SMN1; SMN2 (0.59) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL4746675 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL12914740 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL28730789 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL28730794 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL2713101 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL10989741 | 0.80 | SCN8A (0.49) | LMNASCN8ASCN4ACYP1A2CYP3A4 | |
| SCHEMBL23817559 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |