Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10117589 | 0.86 | SMN1; SMN2 (0.50) | CYP4F2CYP4A11KDM4EL3MBTL1MAPT | |
| SCHEMBL4805882 | 0.85 | ALDH1A1 (0.41) | KDM4ETHRBTDP1L3MBTL1MAPT | |
| SCHEMBL3977128 | 0.84 | L3MBTL1 (0.43) | CYP4F2CYP4A11KDM4ETDP1L3MBTL1 | |
| SCHEMBL11949151 | 0.84 | CSNK2A1 (0.53) | CYP4F2CYP4A11KDM4EL3MBTL1MAPT | |
| SCHEMBL6939626 | 0.84 | CYP4F2 (0.51) | CYP4F2CYP4A11MAPTRAB9APOLB | |
| SCHEMBL8171563 | 0.81 | L3MBTL1 (0.38) | KDM4ETHRBTDP1L3MBTL1MAPT | |
| SCHEMBL1345879 | 0.80 | L3MBTL1 (0.47) | CYP4F2CYP4A11KDM4EL3MBTL1MAPT | |
| SCHEMBL10134991 | 0.75 | CYP4F2 (0.40) | CYP4F2CYP4A11KDM4EL3MBTL1MAPT | |
| SCHEMBL30029152 | 0.73 | ALDH1A1 (0.47) | CYP4F2CYP4A11KDM4EL3MBTL1MAPT | |
| SCHEMBL364121 | 0.73 | ALDH1A1 (0.47) | CYP4F2CYP4A11KDM4EL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |