Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740981 | 0.82 | MEN1 (0.54) | SMN1; SMN2POLBMEN1KMT2AMAPT | |
| SCHEMBL4683961 | 0.81 | MAPK1 (0.41) | SMN1; SMN2POLBKDM4EMEN1KMT2A | |
| SCHEMBL29130752 | 0.81 | AKR1C3 (0.43) | HPGDSMN1; SMN2POLBKDM4EMEN1 | |
| SCHEMBL5183424 | 0.80 | EPHX1 (0.47) | KMT2AALDH1A1 | |
| SCHEMBL5170350 | 0.80 | MEN1 (0.48) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL4232458 | 0.79 | CYP17A1 (0.41) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL5183410 | 0.79 | PKM (0.50) | HPGDPOLBKDM4EMEN1KMT2A | |
| SCHEMBL29131710 | 0.77 | HPGD (0.59) | HPGDSMN1; SMN2POLBMAPTPSMB8 | |
| SCHEMBL30682542 | 0.76 | HPGD (0.55) | HPGDSMN1; SMN2MEN1KMT2APSMB8 | |
| SCHEMBL4238948 | 0.76 | PPARG (0.40) | MAPTATMCYP17A1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |