Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | DDO | Q99489 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18553947 | 0.85 | DAO (0.48) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1882229 | 0.84 | GLA (0.52) | KDM4EHSD17B10ALDH1A1HPGDNPSR1 | |
| SCHEMBL9264392 | 0.83 | DAO (0.64) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3283667 | 0.80 | NSD2 (0.61) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL14127307 | 0.78 | CNR2 (0.46) | KDM4EALDH1A1LMNARXFP1NR4A2 | |
| SCHEMBL31423313 | 0.77 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL3632228 | 0.77 | PADI4 (0.56) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL18553954 | 0.76 | ALDH1A1 (0.47) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL12559601 | 0.76 | DAO (0.71) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4745088 | 0.75 | ALDH1A1 (0.57) | KDM4EHSD17B10ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113006-A1 | METHODS OF USING QUINOLINONE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-18 | — | — | WO | disclosed |