Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306202 | 0.86 | ALDH1A1 (0.55) | HRH4KDM4EGLAGAAMAPT | |
| SCHEMBL2310258 | 0.84 | KDM4E (0.51) | CNR2HRH4IDH1KDM4EGAA | |
| SCHEMBL14115019 | 0.81 | XDH (0.56) | HRH4KDM4EGLAGAAMAPT | |
| SCHEMBL14127119 | 0.79 | CNR2 (0.45) | CNR2KDM4EGLAGAACHEK1 | |
| SCHEMBL4743563 | 0.78 | DAO (0.59) | KDM4EGLAMAPTMEN1KMT2A | |
| SCHEMBL14126804 | 0.77 | CNR2 (0.46) | CNR2KDM4EGLAGAACHEK1 | |
| SCHEMBL22502713 | 0.75 | DAO (0.56) | IDH1KDM4EGLAGAACHEK1 | |
| SCHEMBL3421507 | 0.75 | DAO (0.58) | HRH4IDH1 | |
| SCHEMBL2315591 | 0.75 | ALDH1A1 (0.55) | KDM4EGLAGAAMAPTMEN1 | |
| SCHEMBL17603509 | 0.75 | ALDH1A1 (0.51) | CNR2IDH1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164085-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-12-06 | — | — | WO | disclosed |