Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 13/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743737 | 0.92 | GSR (0.48) | GSRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4747131 | 0.87 | DRD3 (0.39) | GSRDRD3 | |
| SCHEMBL4744753 | 0.87 | ACP1 (0.40) | GSR | |
| SCHEMBL4747855 | 0.86 | DRD3 (0.40) | DRD3 | |
| SCHEMBL4743788 | 0.86 | GSR (0.51) | GSRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4743769 | 0.85 | LCK (0.41) | GSRKDM4EALDH1A1HPGD | |
| SCHEMBL4746265 | 0.79 | GSR (0.61) | GSRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14069128 | 0.75 | MC4R (0.41) | GSRKDM4EALDH1A1 | |
| SCHEMBL4748222 | 0.75 | HRH3 (0.47) | GSRALDH1A1 | |
| SCHEMBL4744848 | 0.75 | GSR (0.40) | GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |