Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 3/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746265 | 0.91 | GSR (0.61) | GSRKDM4EALDH1A1HPGDMAT2A | |
| SCHEMBL4748220 | 0.88 | GSR (0.48) | GSRKDM4EALDH1A1HPGDALOX5 | |
| SCHEMBL4747828 | 0.86 | GSR (0.45) | GSRKDM4EALDH1A1HPGDMAT2A | |
| SCHEMBL4743742 | 0.86 | GSR (0.42) | GSRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4744200 | 0.85 | GSR (0.46) | GSRKDM4EALDH1A1HPGDALOX5 | |
| SCHEMBL4743759 | 0.85 | MPO (0.43) | GSRKDM4EALDH1A1HPGDMAT2A | |
| SCHEMBL4743737 | 0.78 | GSR (0.48) | GSRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4748253 | 0.75 | GSR (0.48) | GSRKDM4EALDH1A1HPGDALOX5 | |
| SCHEMBL4744199 | 0.75 | KCNH2 (0.48) | GSRKDM4EALDH1A1HPGD | |
| SCHEMBL4747565 | 0.75 | GSR (0.48) | GSRKDM4EALDH1A1HPGDMAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |