Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 6/20 | 0.38 |
| ▸ | SCD | O00767 | 4/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747131 | 0.93 | DRD3 (0.39) | DRD3MC4RRAD52SCDLCK | |
| SCHEMBL4743737 | 0.87 | GSR (0.48) | DRD3RAD52 | |
| SCHEMBL4743742 | 0.86 | GSR (0.42) | DRD3 | |
| SCHEMBL4743759 | 0.83 | MPO (0.43) | RPS6KA5 | |
| SCHEMBL4743800 | 0.81 | HRH3 (0.38) | MC4RLCK | |
| SCHEMBL4747828 | 0.76 | GSR (0.45) | — | |
| SCHEMBL4747148 | 0.75 | HRH3 (0.39) | MC4RRAD52LCK | |
| SCHEMBL15909979 | 0.73 | KDM4E (0.43) | — | |
| SCHEMBL4744753 | 0.73 | ACP1 (0.40) | MC4R | |
| SCHEMBL16476450 | 0.72 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |