Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | DRD5 | P21918 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.64 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367224 | 0.84 | HRH3 (0.81) | HRH3HRH4KDM4EALDH1A1MEN1 | |
| SCHEMBL4746250 | 0.84 | HRH3 (0.64) | HRH3HRH4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7371901 | 0.83 | HRH3 (0.79) | HRH3HRH4KDM4EALDH1A1MEN1 | |
| SCHEMBL4743806 | 0.82 | TMEM97 (0.63) | HRH3HRH4KDM4EALDH1A1MEN1 | |
| SCHEMBL4746238 | 0.81 | HRH3 (0.65) | HRH3HRH4KDM4EALDH1A1MEN1 | |
| SCHEMBL4743140 | 0.81 | HRH3 (0.65) | DRD2HRH3HRH4KDM4EALDH1A1 | |
| SCHEMBL4746227 | 0.81 | HRH3 (0.59) | HRH3HRH4KDM4EALDH1A1 | |
| SCHEMBL4743805 | 0.80 | KDM4E (0.69) | HRH3HRH4KDM4EALDH1A1MEN1 | |
| SCHEMBL4743801 | 0.80 | HRH3 (0.59) | DRD2HRH3HRH4MEN1KMT2A | |
| SCHEMBL4743298 | 0.80 | HRH3 (0.59) | HRH3HRH4KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |