Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25540805 | 0.86 | SIGMAR1 (0.72) | HRH3SIGMAR1 | |
| SCHEMBL4743801 | 0.84 | HRH3 (0.59) | HRH3HRH4 | |
| SCHEMBL4743795 | 0.84 | DRD2 (0.66) | HRH3KDM4EALDH1A1HRH4 | |
| SCHEMBL7367224 | 0.83 | HRH3 (0.81) | HRH3KDM4EALDH1A1HRH4 | |
| SCHEMBL4743300 | 0.83 | HRH3 (0.57) | HRH3HRH4 | |
| Hydrochloric Acid SCHEMBL7371901 | 0.82 | HRH3 (0.79) | HRH3KDM4EALDH1A1HRH4 | |
| SCHEMBL4746227 | 0.81 | HRH3 (0.59) | HRH3KDM4EALDH1A1HRH4 | |
| SCHEMBL4745330 | 0.80 | HRH3 (0.60) | HRH3KDM4EALDH1A1HRH4 | |
| SCHEMBL4746696 | 0.80 | HRH3 (0.57) | HRH3HRH4 | |
| SCHEMBL4743806 | 0.80 | TMEM97 (0.63) | HRH3KDM4EALDH1A1HRH4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |