Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.66 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743805 | 0.89 | KDM4E (0.69) | HRH1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4746670 | 0.84 | HRH3 (0.54) | DRD2HRH1KDM4EALDH1A1MEN1 | |
| SCHEMBL7367224 | 0.83 | HRH3 (0.81) | KDM4EALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL28813326 | 0.82 | DRD3 (0.65) | DRD2KCNA5DRD3ALDH1A1MEN1 | |
| SCHEMBL4743801 | 0.82 | HRH3 (0.59) | DRD2HRH1MEN1KMT2AHRH3 | |
| SCHEMBL4743140 | 0.82 | HRH3 (0.65) | DRD2KCNA5HRH1KDM4EALDH1A1 | |
| SCHEMBL4746238 | 0.82 | HRH3 (0.65) | HRH1KDM4EALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7371901 | 0.82 | HRH3 (0.79) | KDM4EALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL4746235 | 0.81 | HRH3 (0.55) | DRD2HRH1MEN1KMT2AHRH3 | |
| SCHEMBL4746696 | 0.80 | HRH3 (0.57) | DRD2HRH1MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |