Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743805 | 0.86 | KDM4E (0.69) | HRH3HRH1HRH4KDM4EALDH1A1 | |
| SCHEMBL4743802 | 0.84 | DRD2 (0.66) | HRH3HRH1HRH4KDM4EALDH1A1 | |
| SCHEMBL7367224 | 0.80 | HRH3 (0.81) | HRH3HRH4KDM4EALDH1A1MEN1 | |
| SCHEMBL4746238 | 0.79 | HRH3 (0.65) | HRH3HRH1HRH4KDM4EALDH1A1 | |
| SCHEMBL4743140 | 0.79 | HRH3 (0.65) | HRH3HRH1HRH4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7371901 | 0.79 | HRH3 (0.79) | HRH3HRH4KDM4EALDH1A1MEN1 | |
| SCHEMBL4743298 | 0.78 | HRH3 (0.59) | HRH3HRH1HRH4KDM4EALDH1A1 | |
| SCHEMBL4743801 | 0.78 | HRH3 (0.59) | HRH3HRH1HRH4MEN1KMT2A | |
| SCHEMBL4747531 | 0.76 | DRD2 (0.58) | HRH3HRH1HRH4MEN1KMT2A | |
| SCHEMBL4746235 | 0.76 | HRH3 (0.55) | HRH3HRH1HRH4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |