Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745415 | 0.97 | HRH4 (0.56) | HRH4KDM4EALDH1A1HRH3BCHE | |
| SCHEMBL4744547 | 0.93 | HRH4 (0.60) | HRH4KDM4EALDH1A1HRH3BCHE | |
| SCHEMBL4743821 | 0.89 | HRH4 (0.48) | HRH4KDM4EALDH1A1HRH3BCHE | |
| SCHEMBL4743823 | 0.83 | HRH4 (0.51) | HRH4KDM4EALDH1A1HRH3BCHE | |
| SCHEMBL4743808 | 0.81 | HRH4 (0.64) | HRH4KDM4EALDH1A1HRH3 | |
| SCHEMBL4744548 | 0.77 | HRH4 (0.58) | HRH4KDM4EALDH1A1HRH3BCHE | |
| SCHEMBL4746228 | 0.76 | DRD2 (0.69) | HRH4ALDH1A1HRH3 | |
| SCHEMBL4745418 | 0.75 | HRH4 (0.55) | HRH4KDM4EALDH1A1HRH3BCHE | |
| SCHEMBL4743805 | 0.75 | KDM4E (0.69) | HRH4KDM4EALDH1A1HRH3BCHE | |
| SCHEMBL7367224 | 0.73 | HRH3 (0.81) | HRH4KDM4EALDH1A1HRH3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |