Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 17/20 | 0.54 |
| ▸ | PPARG | P37231 | 16/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744629 | 0.97 | KDR (0.62) | KDRPPARAPPARGFFAR1CYP2C9 | |
| SCHEMBL4743666 | 0.96 | KDR (0.60) | KDRPPARAPPARGFFAR1CYP2C9 | |
| SCHEMBL4748548 | 0.91 | PPARG (0.55) | KDRPPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL4748098 | 0.88 | PPARA (0.52) | PPARAPPARG | |
| SCHEMBL4744642 | 0.88 | PPARG (0.55) | KDRPPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL4747104 | 0.87 | PPARA (0.48) | KDRPPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL4744698 | 0.86 | FFAR1 (0.63) | KDRPPARAPPARGFFAR1 | |
| SCHEMBL4745030 | 0.84 | PPARG (0.59) | PPARAPPARGFFAR1 | |
| SCHEMBL4743967 | 0.84 | PPARA (0.49) | KDRPPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL27650834 | 0.82 | KDR (0.74) | KDRPPARAPPARGFFAR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |