Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.48 |
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743967 | 0.98 | PPARA (0.49) | PPARAPPARGKDRALDH1A1LMNA | |
| SCHEMBL4744571 | 0.94 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL4743931 | 0.87 | KDR (0.61) | PPARAPPARGKDRCYP2C9KCNH2 | |
| SCHEMBL4744629 | 0.84 | KDR (0.62) | PPARAPPARGKDRCYP2C9KCNH2 | |
| SCHEMBL4748548 | 0.83 | PPARG (0.55) | PPARAPPARGKDRMAPTCYP2C9 | |
| SCHEMBL4743666 | 0.83 | KDR (0.60) | PPARAPPARGKDRMAPTCYP2C9 | |
| SCHEMBL4744642 | 0.82 | PPARG (0.55) | PPARAPPARGKDRCYP2C9KCNH2 | |
| SCHEMBL4748098 | 0.81 | PPARA (0.52) | PPARAPPARG | |
| SCHEMBL4747247 | 0.79 | POLB (0.62) | PPARAPPARGKDRALDH1A1LMNA | |
| SCHEMBL4747541 | 0.78 | KDM4E (0.53) | PPARAPPARGKDRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |