Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743532 | 0.92 | GFER (0.70) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4746660 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4745889 | 0.91 | KMT2A (0.66) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4748024 | 0.91 | CA1 (0.67) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4747965 | 0.89 | KMT2A (0.56) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4746722 | 0.88 | KMT2A (0.54) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4747296 | 0.88 | KMT2A (0.54) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4743907 | 0.88 | KMT2A (0.55) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4745883 | 0.88 | KMT2A (0.55) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4747343 | 0.88 | KMT2A (0.58) | ALDH1A1HTTNPSR1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |