Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743949 | 0.91 | ALDH1A1 (0.64) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4743532 | 0.90 | GFER (0.70) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4748024 | 0.89 | CA1 (0.67) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4747965 | 0.87 | KMT2A (0.56) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4745883 | 0.86 | KMT2A (0.55) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4743907 | 0.86 | KMT2A (0.55) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4743528 | 0.86 | KMT2A (0.74) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4747343 | 0.86 | KMT2A (0.58) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4743906 | 0.86 | CA1 (0.57) | ALDH1A1HTTNPSR1GFERKMT2A | |
| SCHEMBL4745908 | 0.86 | CA1 (0.63) | ALDH1A1HTTNPSR1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |