Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA4 | P22748 | 4/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL540831 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL28271586 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL3001932 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL11339920 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL2467383 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL28282273 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL28402400 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL27606778 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL16432302 | 0.90 | LMNA (0.47) | FFAR3LCKFYNLMNACA1 | |
| Phosphoric Acid SCHEMBL4743959 | 0.89 | SLC34A1 (0.53) | FFAR3LCKFYNLMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2691411-B1 | BUFFER SYSTEM FOR PROTEIN PURIFICATION | GLAXOSMITHKLINE LLC (US) | 2020-02-26 | — | — | EP | disclosed |
| CN-106432648-B | A kind of environment-friendly preparation method thereof of vinyl chloride/N, N- dimethacrylamide copolymer | 宁波大学 | 2018-10-23 | — | — | CN | disclosed |
| CN-107915769-A | Buffer solution system for protein purification | 葛兰素史密斯克莱有限责任公司 | 2018-04-17 | — | — | CN | disclosed |
| US-9902837-B2 | Oil extended functionalized styrene-butadiene copolymer | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-02-27 | — | — | US | disclosed |
| US-9868761-B2 | Buffer system for protein purification | GLAXOSMITHKLINE LLC (US) | 2018-01-16 | — | — | US | disclosed |
| CN-105121476-B | Oil extended functionalized styrene-butadiene copolymers | 阿朗新科德国有限责任公司 | 2018-01-02 | — | — | CN | disclosed |
| EP-2986647-B1 | OIL EXTENDED FUNCTIONALIZED STYRENE-BUTADIENE COPOLYMER | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-20170174721-A1 | BUFFER SYSTEM FOR PROTEIN PURIFICATION | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-06-22 | — | — | US | disclosed |
| US-9624261-B2 | Buffer system for protein purification | GLAXOSMITHKLINE LLC (US) | 2017-04-18 | — | — | US | disclosed |
| CN-106432648-A | Green preparation method of vinyl chloride-N,N-dimethyl acrylamide copolymer | 宁波大学 | 2017-02-22 | — | — | CN | disclosed |
| EP-2792689-A1 | Oil extended functionalized styrene-butadiene copolymer | LANXESS Deutschland GmbH (DE) | 2014-10-22 | — | — | EP | disclosed |
| EP-2691411-A1 | BUFFER SYSTEM FOR PROTEIN PURIFICATION | GlaxoSmithKline LLC (US) | 2014-02-05 | — | — | EP | disclosed |
| CN-103547589-A | Buffer system for protein purification | GLAXOSMITHKLINE LLC | 2014-01-29 | — | — | CN | disclosed |
| US-20140018525-A1 | BUFFER SYSTEM FOR PROTEIN PURIFICATION | GLAXOSMITHKLINE LLC (US) | 2014-01-16 | — | — | US | disclosed |
| WO-2012135415-A1 | BUFFER SYSTEM FOR PROTEIN PURIFICATION | GLAXOSMITHKLINE LLC (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |
| US-5207609-A | Buffered acid-treated food casing | VISKASE CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
| US-5207608-A | Buffered acid-treated food casing | VISKASE CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
| US-5108804-A | Cellulosic; denatured outer skin with bloom; high speed peeling after chilling; encased raw pork-containing product; distortion resistance | VISKASE CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |