Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744081 | 0.94 | MCHR1 (0.38) | MCHR1ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL4228379 | 0.90 | MCHR1 (0.41) | MCHR1ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL4232410 | 0.90 | PKM (0.39) | ALDH1A1MAPTKMT2AKDM4ETSHR | |
| SCHEMBL4234367 | 0.90 | SSTR5 (0.42) | SSTR5MCHR1ALDH1A1MAPTPOLB | |
| SCHEMBL4240513 | 0.84 | MCHR1 (0.40) | MCHR1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL4240511 | 0.83 | SSTR5 (0.42) | SSTR5MCHR1ALDH1A1MAPTKMT2A | |
| SCHEMBL4683520 | 0.83 | PKM (0.39) | MCHR1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL4238698 | 0.82 | CCR5 (0.47) | MCHR1ALDH1A1MAPTKMT2ACCR5 | |
| SCHEMBL4238693 | 0.82 | CHRM4 (0.47) | SSTR5MCHR1ALDH1A1MAPTKMT2A | |
| SCHEMBL4687107 | 0.80 | MAPT (0.41) | MCHR1MAPTPOLBKMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |