Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.30 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | NOS2 | P35228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26151467 | 1.00 | NOS3 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL15679323 | 0.85 | — | — | |
| SCHEMBL2154499 | 0.85 | CA1 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL14258652 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL8016547 | 0.82 | CA1 (0.31) | NOS3NOS1NOS2 | |
| SCHEMBL597925 | 0.79 | — | — | |
| SCHEMBL598873 | 0.79 | — | — | |
| SCHEMBL598874 | 0.79 | — | — | |
| SCHEMBL597926 | 0.79 | — | — | |
| SCHEMBL597924 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964259-B2 | Catalyst composition for hydrogenating 4,4′-methylenedianiline derivatives and method for preparing 4,4′-methylene bis(cyclohexylamine) derivatives using the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2024-04-23 | — | — | US | claimed |
| US-20210197177-A1 | CATALYST COMPOSITION FOR HYDROGENATING 4,4'-METHYLENEDIANILINE DERIVATIVES AND METHOD FOR PREPARING 4,4'-METHYLENE BIS(CYCLOHEXYLAMINE) DERIVATIVES USING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2021-07-01 | — | — | US | claimed |
| CN-112824435-A | High-regularity thermoplastic polyurethane material and preparation method thereof | 北京化工大学 | 2021-05-21 | — | — | CN | claimed |
| CN-108610466-B | Polyurea elastomer with polysiloxane completely replacing polyether and preparation method thereof | 山东大学 | 2021-04-06 | — | — | CN | claimed |
| CN-108219146-A | A kind of organic-silicon-modified polyureas（Polyurethane）Elastomer and preparation method thereof | 山东大学 | 2018-06-29 | — | — | CN | claimed |
| CN-101602839-B | Integral skin polyurethane-urea composition, preparation method and application thereof | SHANGHAI HEDA POLYMERIC TECHNOLOGY CO LTD | 2011-04-13 | — | — | CN | claimed |
| CN-101602839-A | A kind of integral skin polyurethane-urea composition, its preparation method and application | SHANGHAI HEDA POLYMERIC TECHNO (CN) | 2009-12-16 | — | — | CN | claimed |
| US-4252742-A | USING A BED OF GROUP 8 METAL CATALYST, AMMONIA, AND HYDROGEN, AND HIGH PRESSURE AND TEMPERATURE | CIBA-GEIGY CORPORATION (US) | 1981-02-24 | — | — | US | claimed |
| US-11964259-B2 | Catalyst composition for hydrogenating 4,4′-methylenedianiline derivatives and method for preparing 4,4′-methylene bis(cyclohexylamine) derivatives using the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2024-04-23 | — | — | US | disclosed |
| US-20210197177-A1 | CATALYST COMPOSITION FOR HYDROGENATING 4,4'-METHYLENEDIANILINE DERIVATIVES AND METHOD FOR PREPARING 4,4'-METHYLENE BIS(CYCLOHEXYLAMINE) DERIVATIVES USING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2021-07-01 | — | — | US | disclosed |
| CN-112824435-A | High-regularity thermoplastic polyurethane material and preparation method thereof | 北京化工大学 | 2021-05-21 | — | — | CN | disclosed |
| CN-108610466-B | Polyurea elastomer with polysiloxane completely replacing polyether and preparation method thereof | 山东大学 | 2021-04-06 | — | — | CN | disclosed |
| CN-109517333-B | Solvent-free resin composition and use thereof | 台燿科技股份有限公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-110591046-A | Cross-linked ester-soluble polyurethane ink binder, and preparation method and application thereof | 黄山中泽新材料有限公司 | 2019-12-20 | — | — | CN | disclosed |
| US-4399163-A | ARTIFICIAL SWEETENERS | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0022751-B1 | PROCESS FOR THE PRODUCTION OF 2,6-DIALKYLCYCLOHEXYLAMINES | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | disclosed |
| EP-0069811-A1 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1983-01-19 | — | — | EP | disclosed |
| EP-0034876-A2 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4252742-A | USING A BED OF GROUP 8 METAL CATALYST, AMMONIA, AND HYDROGEN, AND HIGH PRESSURE AND TEMPERATURE | CIBA-GEIGY CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
| EP-0022751-A1 | Process for the production of 2,6-dialkylcyclohexylamines | CIBA-GEIGY AG (CH) | 1981-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964259-B2 | Catalyst composition for hydrogenating 4,4′-methylenedianiline derivatives and method for preparing 4,4′-methylene bis(cyclohexylamine) derivatives using the same | HNMT, MCM4, HRH3 | NOS3 2222/4885NOS1 1723/4885NOS2 1245/4885 |
| US-20210197177-A1 | CATALYST COMPOSITION FOR HYDROGENATING 4,4'-METHYLENEDIANILINE DERIVATIVES AND METHOD FOR PREPARING 4,4'-METHYLENE BIS(CYCLOHEXYLAMINE) DERIVATIVES USING THE SAME | HNMT, HRH3, MCM4 | NOS3 2230/4885NOS1 1713/4885NOS2 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.