Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1020369 | 0.98 | IDO1 (0.50) | IDO1PNMTALDH1A1HPGDTAAR1 | |
| Hydrochloric Acid SCHEMBL7824228 | 0.95 | IDO1 (0.48) | IDO1PNMTALDH1A1HPGDTAAR1 | |
| SCHEMBL15863104 | 0.83 | DPP4 (0.59) | IDO1PNMTALDH1A1HPGDTAAR1 | |
| SCHEMBL310847 | 0.80 | PNMT (0.56) | IDO1PNMTALDH1A1HPGDTAAR1 | |
| SCHEMBL29763190 | 0.80 | PNMT (0.56) | IDO1PNMTALDH1A1HPGDTAAR1 | |
| SCHEMBL1945874 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP1A2GRIA1CACNG8 | |
| SCHEMBL29809738 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP1A2GRIA1CACNG8 | |
| SCHEMBL1294116 | 0.78 | GRIA1 (0.43) | IDO1PNMTALDH1A1HPGDTAAR1 | |
| SCHEMBL2744577 | 0.77 | GRIA1 (0.42) | IDO1PNMTALDH1A1HPGDTAAR1 | |
| SCHEMBL1396993 | 0.77 | ALDH1A1 (0.43) | PNMTALDH1A1HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |