Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | GFER | P55789 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746786 | 0.93 | KMT2A (0.62) | KMT2AGFERCA1CA2CA9 | |
| SCHEMBL4743939 | 0.92 | ALDH1A1 (0.61) | KMT2AGFERCA1CA2CA9 | |
| SCHEMBL4747945 | 0.89 | KMT2A (0.53) | KMT2AGFERCA1CA2CA9 | |
| SCHEMBL14069571 | 0.89 | KMT2A (0.56) | KMT2AGFERCA1CA2CA9 | |
| SCHEMBL4743511 | 0.88 | KMT2A (0.55) | KMT2AGFERCA1CA2CA9 | |
| SCHEMBL4743988 | 0.88 | GFER (0.57) | KMT2AGFERCA1CA2CA9 | |
| SCHEMBL4746803 | 0.88 | KMT2A (0.70) | KMT2AGFERALDH1A1HTTNPSR1 | |
| SCHEMBL4746692 | 0.88 | KMT2A (0.55) | KMT2AGFERCA1CA2CA9 | |
| SCHEMBL4743915 | 0.88 | KMT2A (0.55) | KMT2AGFERCA1CA2CA9 | |
| SCHEMBL4743568 | 0.87 | KMT2A (0.53) | KMT2AGFERCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |