Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747938 | 0.85 | HTR7 (0.73) | HTR7 | |
| SCHEMBL4747970 | 0.85 | KMT2A (0.61) | HTR7CYP3A4CYP2C19KMT2A | |
| SCHEMBL4747942 | 0.85 | KMT2A (0.74) | HTR7CYP3A4CYP2C19KMT2A | |
| SCHEMBL19306066 | 0.84 | HTR7 (0.81) | HTR7 | |
| SCHEMBL30876409 | 0.83 | HTR7 (1.00) | HTR7 | |
| SCHEMBL19306044 | 0.83 | HTR7 (1.00) | HTR7 | |
| SCHEMBL4746803 | 0.82 | KMT2A (0.70) | HTR7CYP3A4CYP2C19KMT2A | |
| SCHEMBL19306464 | 0.81 | HTR7 (1.00) | HTR7KMT2A | |
| SCHEMBL19317334 | 0.81 | HTR7 (0.83) | HTR7CYP3A4CYP2C19KMT2A | |
| SCHEMBL30876370 | 0.81 | HTR7 (1.00) | HTR7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |