Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747945 | 0.90 | KMT2A (0.53) | HTR7GFERKMT2ACACNA1BALDH1A1 | |
| SCHEMBL4743977 | 0.90 | KMT2A (0.50) | HTR7GFERKMT2ACACNA1BALDH1A1 | |
| SCHEMBL27881749 | 0.90 | GFER (0.61) | HTR7GFERKMT2ACACNA1BPOLB | |
| SCHEMBL4747970 | 0.89 | KMT2A (0.61) | HTR7GFERKMT2ACACNA1BPOLB | |
| SCHEMBL4745907 | 0.85 | GFER (0.51) | HTR7GFERKMT2ACACNA1BPOLB | |
| SCHEMBL4746661 | 0.84 | HTR7 (0.49) | HTR7GFERKMT2ACACNA1BPOLB | |
| SCHEMBL4744248 | 0.84 | HTR7 (0.49) | HTR7GFERKMT2ACACNA1BPOLB | |
| SCHEMBL4744263 | 0.84 | HTR7 (0.58) | HTR7GFERKMT2ACACNA1BPOLB | |
| SCHEMBL5152712 | 0.84 | GFER (0.50) | HTR7GFERKMT2APOLBALDH1A1 | |
| SCHEMBL4743953 | 0.83 | GFER (0.60) | HTR7GFERKMT2ACACNA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |