Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744306 | 0.90 | HTR7 (0.53) | KMT2AHTR7GFERCA1CA2 | |
| SCHEMBL4747945 | 0.88 | KMT2A (0.53) | KMT2AHTR7GFERCA1CA2 | |
| SCHEMBL4747311 | 0.83 | CA1 (0.54) | KMT2AHTR7GFERCA1CA2 | |
| SCHEMBL4743953 | 0.83 | GFER (0.60) | KMT2AHTR7GFERCA1CA2 | |
| SCHEMBL4747931 | 0.83 | HTR7 (0.53) | KMT2AHTR7GFERCA1CA2 | |
| SCHEMBL4743939 | 0.83 | ALDH1A1 (0.61) | KMT2AHTR7GFERCA1CA2 | |
| SCHEMBL4747942 | 0.81 | KMT2A (0.74) | KMT2AHTR7GFERALDH1A1MEN1 | |
| SCHEMBL4747356 | 0.81 | HTR7 (0.51) | KMT2AHTR7GFERCA1CA2 | |
| SCHEMBL4746657 | 0.80 | CA1 (0.57) | KMT2AHTR7GFERCA1CA2 | |
| SCHEMBL4743942 | 0.80 | HTR7 (0.59) | KMT2AHTR7GFERCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |