Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749202 | 0.83 | LMNA (0.43) | LMNAMAPTL3MBTL1POLBKMT2A | |
| SCHEMBL26998829 | 0.79 | KDM4E (0.38) | MAPTKMT2A | |
| SCHEMBL4748400 | 0.78 | MAPT (0.52) | LMNAMAPTL3MBTL1POLBCYP1A2 | |
| SCHEMBL25380852 | 0.76 | CYP3A4 (0.37) | MAPTL3MBTL1 | |
| SCHEMBL2092537 | 0.76 | CYP2A6 (0.33) | LMNAMEN1KMT2APARP1 | |
| SCHEMBL11088559 | 0.76 | MAPT (0.60) | LMNAMAPTL3MBTL1POLBCYP1A2 | |
| SCHEMBL5022784 | 0.76 | LMNA (0.51) | LMNAMAPTL3MBTL1POLBCYP1A2 | |
| SCHEMBL5412870 | 0.73 | MAPT (0.47) | LMNAMAPTL3MBTL1POLBCYP1A2 | |
| SCHEMBL10754312 | 0.73 | PARP1 (0.47) | LMNAMAPTL3MBTL1POLBMEN1 | |
| SCHEMBL11846851 | 0.72 | LMNA (0.44) | LMNAMAPTL3MBTL1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |