Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19347407 | 0.79 | TSHR (0.49) | TSHRHTTHPGDMAPK1CYP1A2 | |
| SCHEMBL4765741 | 0.79 | KMT2A (0.65) | HTTHPGDMAPK1CYP1A2CHRNB2 | |
| SCHEMBL3954844 | 0.79 | EGLN1 (0.46) | TSHRHTTKMT2A | |
| SCHEMBL18586564 | 0.78 | HPGD (0.62) | HPGDCYP1A2SMN1; SMN2 | |
| SCHEMBL791333 | 0.77 | GAA (0.57) | — | |
| SCHEMBL29469069 | 0.77 | GAA (0.57) | — | |
| SCHEMBL23169262 | 0.77 | TSHR (0.68) | TSHRHTTHPGDHCRTR1SMN1; SMN2 | |
| SCHEMBL19347405 | 0.77 | HTT (0.54) | TSHRHTTHPGDHCRTR1SMN1; SMN2 | |
| SCHEMBL31255732 | 0.76 | GAA (0.37) | TSHRHTTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL31255734 | 0.76 | GAA (0.37) | TSHRHTTHPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104597-A2 | SULFONYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | WO | disclosed |