Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487361 | 1.00 | DPP4 (0.54) | DPP4LMNAMAPK1EPHX1BCAT2 | |
| SCHEMBL487568 | 1.00 | DPP4 (0.54) | DPP4LMNAMAPK1EPHX1BCAT2 | |
| SCHEMBL487880 | 1.00 | DPP4 (0.54) | DPP4LMNAMAPK1EPHX1BCAT2 | |
| SCHEMBL4884477 | 1.00 | DPP4 (0.54) | DPP4LMNAMAPK1EPHX1BCAT2 | |
| SCHEMBL4887191 | 1.00 | DPP4 (0.54) | DPP4LMNAMAPK1EPHX1BCAT2 | |
| Hydrochloric Acid SCHEMBL487925 | 0.98 | DPP4 (0.52) | DPP4LMNAMAPK1EPHX1BCAT2 | |
| SCHEMBL939042 | 0.84 | DPP4 (0.56) | DPP4LMNAMAPK1ADRA2AADRA2C | |
| SCHEMBL8058962 | 0.84 | DPP4 (0.56) | DPP4LMNAMAPK1ADRA2AADRA2C | |
| SCHEMBL5860807 | 0.84 | DPP4 (0.56) | DPP4LMNAMAPK1ADRA2AADRA2C | |
| SCHEMBL4073511 | 0.84 | DPP4 (0.56) | DPP4LMNAMAPK1ADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101608-A1 | PROCESS FOR THE PREPARATION OF (2R,3S)-3-PHENYLISOSERINE METHYL ESTER ACETATE SALT | INDENA S.P.A. (IT) | 2008-08-28 | — | — | WO | disclosed |