Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860807 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL939043 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL4073511 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL939042 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL487425 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL6027457 | 0.98 | DPP4 (0.54) | DPP4LMNAMAPK1CYP2D6SRC | |
| Hydrochloric Acid SCHEMBL5860803 | 0.98 | DPP4 (0.54) | DPP4LMNAMAPK1CYP2D6SRC | |
| Hydrochloric Acid SCHEMBL8073692 | 0.98 | DPP4 (0.54) | DPP4LMNAMAPK1CYP2D6SRC | |
| Hydrochloric Acid SCHEMBL3184809 | 0.98 | DPP4 (0.54) | DPP4LMNAMAPK1CYP2D6SRC | |
| Cadaverine Tartrate SCHEMBL30110790 | 0.91 | DPP4 (0.64) | DPP4LMNAMAPK1CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008054233-A2 | PROCESS FOR THE PREPARATION OF DOCETAXEL | INSTYTUT FARMACEUTYCZNY (PL) | 2008-05-08 | — | — | WO | disclosed |
| EP-0844992-B1 | PROCESS FOR PRODUCING BETA-AMINO-ALPHA-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | DEGUSSA (DE) | 2000-05-24 | — | — | EP | disclosed |
| US-5932758-A | Process for the production β-amino-α-hydroxycarboxylic acids and derivatives thereof | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |
| US-5932758-A | Process for the production β-amino-α-hydroxycarboxylic acids and derivatives thereof | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |
| EP-0844992-A1 | PROCESS FOR PRODUCING $g(b)-AMINO-$g(a)-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | Degussa Aktiengesellschaft (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997002236-A1 | PROCESS FOR PRODUCING β-AMINO-α-HYDROXYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-01-23 | — | — | WO | disclosed |