Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178888 | 0.87 | CYP2A6 (0.58) | APPALDH1A1MAPTCYP2A6CYP2A13 | |
| Bromide SCHEMBL8864770 | 0.85 | CYP2A6 (0.56) | APPALDH1A1MAPTCYP2A6CYP2A13 | |
| Hydrochloric Acid SCHEMBL2806293 | 0.85 | CYP2A6 (0.56) | APPALDH1A1MAPTCYP2A6CYP2A13 | |
| SCHEMBL18664601 | 0.81 | CYP2A6 (0.52) | APPALDH1A1MAPTCYP2A6CYP2A13 | |
| SCHEMBL13857829 | 0.81 | RELA (0.65) | APPALDH1A1MAPTCYP2A6CYP2A13 | |
| SCHEMBL13857827 | 0.81 | RELA (0.65) | APPALDH1A1MAPTCYP2A6CYP2A13 | |
| SCHEMBL21294111 | 0.79 | APP (0.50) | APPALDH1A1MAPTCYP2A6CYP2A13 | |
| SCHEMBL10338213 | 0.77 | SLC2A1 (0.70) | APPALDH1A1MAPTCYP2A6CYP2A13 | |
| SCHEMBL279039 | 0.77 | MAOB (0.49) | ALDH1A1MAPTHPGDKMT2AHSD17B3 | |
| SCHEMBL8740584 | 0.76 | ALDH1A1 (0.68) | APPALDH1A1MAPTCYP2A6CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109008-A1 | ENDOTRACHEAL CUFF AND TECHNIQUE FOR USING THE SAME | NELLCOR PURITAN BENNETT LLC (US) | 2008-09-12 | — | — | WO | disclosed |
| US-20080210243-A1 | Endotracheal cuff and technique for using the same | COVIDIEN LP | 2008-09-04 | — | — | US | disclosed |
| US-7066904-B2 | Triggered release hydrogel drug delivery system | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2006-06-27 | — | — | US | disclosed |
| US-20030114791-A1 | Triggered release hydrogel drug delivery system | BOSTON SCIENTIFIC SCIMED, INC. | 2003-06-19 | — | — | US | disclosed |
| US-6524274-B1 | Triggered release hydrogel drug delivery system | SCIMED LIFE SYSTEMS, INC. | 2003-02-25 | — | — | US | disclosed |
| EP-0836429-A4 | TRIGGERED RELEASE DRUG DELIVERY SYSTEM | BOSTON SCIENT CORP (US) | 1998-12-16 | — | — | EP | disclosed |
| EP-0836429-A1 | TRIGGERED RELEASE DRUG DELIVERY SYSTEM | BOSTON SCIENTIFIC CORPORATION (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1996039949-A1 | TRIGGERED RELEASE DRUG DELIVERY SYSTEM | BOSTON SCIENTIFIC CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |