Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5112831 | 0.84 | KMT2A (0.45) | HTTKMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4711518 | 0.78 | KMT2A (0.44) | HTTKMT2AMEN1 | |
| SCHEMBL8130253 | 0.74 | HTT (0.50) | HTTRECQLKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL20927103 | 0.73 | HTT (0.49) | HTTKMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL968488 | 0.71 | HTT (1.00) | HTTRECQLKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27638780 | 0.70 | TSHR (0.55) | RECQLKMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8429732 | 0.68 | SMN1; SMN2 (0.72) | HTTKMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27611556 | 0.67 | KDM4E (0.45) | HTTRECQLKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL23768210 | 0.67 | HTT (0.42) | HTTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7976882 | 0.67 | HTT (0.55) | HTTRECQLKMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |